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Based on these results, the International Agency for International Research on Cancer (IARC) and US-EPA classified DEHP as a possible carcinogen (2 B substance suspected of causing cancer), subject to multiple mechanisms and pathways simultaneously involved, related to a non-genotoxic Mode of Action (MoA) ( In addition to in vivo carcinogenicity data, controversial results were obtained by testing DEHP in cell transformation assays (CTAs) (Supplementary Table S1)
Key Scientific Features & Chemical Profile of BPC-157 & TB-500 Molecular Data Analytical Verification Core Analytical Procedures: High-Performance Liquid Chromatography (HPLC) Core Analytical Procedures: Mass Spectrometry (MS) The 6X Safety Testing Protocol Heavy Metals Screening : Detects trace elements like lead, arsenic, or mercury that can inadvertently enter the supply chain during chemical synthesis
doi: 10.3389/fpls.2023.1216682 Summary Keywords glucoraphanin, sulforaphane, Nrf2 signaling, ferroptosis, tumor microenvironment Citation Zhao Z, Chen Q, Qiao X, Wang J, Ali ZTA, Li J and Yin L (2025) Sulforaphane in cancer precision medicine: from biosynthetic origins to multiscale mechanisms and clinical translation